Wikipedia gpewiki https://gpe.wikipedia.org/wiki/Main_Page MediaWiki 1.47.0-wmf.12 first-letter Media Special Talk User User talk Wikipedia Wikipedia talk File File talk MediaWiki MediaWiki talk Template Template talk Help Help talk Category Category talk TimedText TimedText talk Module Module talk Event Event talk 0 28829 107903 107855 2026-07-26T11:44:50Z DaSupremo 9 Make sum corrections 107903 wikitext text/x-wiki {{Infobox comic strip | title = Casey and Andy | image = | caption = De official logo of de series. | author = [[Andy Weir]] | url = [http://www.galactanet.com/comic/allstrips.php Galactanet] | rss = | atom = | status = Dem fini<ref>{{Cite web |last=Garratt |first=Sheryl |date=26 August 2019 |title=Andy Weir on writing an accidental best-seller |url=https://thecreativelife.net/the-martian-andy-weir-on-writing-an-accidental-best-seller |access-date=26 August 2019 |website=The Creative Life |archive-date=17 September 2021 |archive-url=https://web.archive.org/web/20210917120320/https://thecreativelife.net/the-martian-andy-weir-on-writing-an-accidental-best-seller/ |url-status=live }}</ref> | first = {{br separated entries|28 February 2001|[http://www.galactanet.com/comic/view.php?strip=1 Strip 1]}} | last = {{br separated entries|25 August 2008|[http://www.galactanet.com/comic/view.php?strip=666 Epilogue]}} | syndicate = | publisher = [[LiveJournal]], [[Galactanet]] | genre = [[Action genre|Action]], comedy, [[superhero fiction|superhero]] | rating = | preceded by = | followed by = [[Cheshire Crossing]] }} '''''Casey and Andy''''' (wey dem dey stylize am as '''''Casey & Andy''''', or simply '''''C&A''''') be one [[webcomic]] series wey [[Andy Weir]] wrep den draw. De story dey follow de adventures of two mad scientists (fictional versions of Weir einself den ein best paddie [[Casey Grimm]]) plus dema paddy-dem den oda people wey dem know, like writer [[Jennifer Brozek]]. Dem update de comic three times every week for early 2000s—Monday, Wednesday, den Friday. Most of de time de comic dey use gag-a-comic style, buh e still get long-running storylines den running gags.<ref>{{Cite news |last=Ashley |first=Berty |date=28 October 2022 |title=Quiz — Easy Like Sunday Morning |work=[[The Hindu]] |url=https://www.thehindu.com/books/easy-like-sunday-morning-quiz-berty-ashley/article66039436.ece |access-date=28 October 2022 |quote=[[Andy Weir]] authored a humour [[Webcomic|web comic]] called ''Casey and Andy'', featuring fictionalised ‘mad scientist’ versions of himself and his friends.}}</ref> De comic get strong science den history vibe, plus plenty facts wey come from sources wey no be everybro wey know. E too show say plenty tins wey happen for Weir den Grimm dema real lives resemble wat dey happen insyd de comic. Some strips saf take inspiration from real events wey happen around dat time, like de [[Opportunity mission timeline|''Opportunity'' mission to Mars]], de [[2003 invasion of Iraq]], den de [[2004 United States presidential election]]. Later, dem turn de strip into one [[roleplaying game]] wey dem call ''[[GURPS Casey and Andy]]'' under de [[GURPS]] system. [[David Morgan-Mar]] work on am plus Weir, den [[Steve Jackson Games]] publish one [[PDF]] [[Sourcebook (gaming)|sourcebook]] give am. For 1 May 2006, Weir announce say de strip go end for Strip 666. E talk say e start dey feel too much pressure to make every strip reach de standard wey he want, den he fear say de humor go reduce. He san want get more time make he fit work on ''[[Cheshire Crossing]]'', ein new webcomic project. ''Casey and Andy'' finally end plus ein 666th strip for 25 August 2008. Later, de character Bob appear insyd Weir ein 2017 novel ''[[Artemis (novel)|Artemis]]''.<ref name="AMA">{{Cite web |date=4 December 2017 |title=I am Andy Weir, author of ''The Martian'', and my new book ''Artemis'', out now. AMA! |url=https://www.reddit.com/r/books/comments/7hjh84/i_am_andy_weir_author_of_the_martian_and_my_new/dqrflj2 |access-date=4 December 2017 |website=[[Reddit]] |quote='''u/ManyThingsDeck''': Is the character Bob in ''[[Artemis (novel)|Artemis]]'' an in-joke for your friends who know the story of "And Bob was there too"? '''u/sephalon''': I planned to do that, but later I forgot to put "Bob was there, too" in the book! :( |archive-date=7 January 2022 |archive-url=https://web.archive.org/web/20220107045600/https://www.reddit.com/r/books/comments/7hjh84/i_am_andy_weir_author_of_the_martian_and_my_new/dqrflj2/ |url-status=live }}</ref> For 31 December 2021, dem create one ''Casey and Andy'' subreddit, wey David Morgan-Mar, Casey Grimm, den John Gillman dey oversee, plus Weir ein approval. Dem create am for de social news den discussion website Reddit. Later, de subreddit publish one official crossover comic plus Tredlocity ein science fantasy webcomic ''Val and Isaac'' for January 2022. De comic feature de character Space Dread as de main character. Dem san release one authorised offline-accessible Mega archive of de webcomic.<ref>{{Cite web |date=1 January 2022 |title=A tribute to ''Casey and Andy'', by u/tredlocity (feat. Space Dread) |url=https://www.reddit.com/r/CaseyAndAndy/comments/rt8mm0/a_tribute_to_casey_and_andy_by_utredlocity_feat |access-date=1 January 2022 |website=[[Reddit]]}}</ref><ref>{{Cite web |last=Grimm |first=Casey |author-link=Casey Grimm |date=15 January 2022 |title=''Casey and Andy'' Index — Casey's Webcomics |url=http://gamergeek.org/c_and_a_index.html |access-date=15 January 2022 |website=Gamer Geek |archive-date=21 August 2024 |archive-url=https://web.archive.org/web/20240821192631/http://gamergeek.org/c_and_a_index.html |url-status=live }}</ref><ref>{{Cite web |date=15 January 2022 |title=An index I assembled from a post in the now-dead forum, salvaged thanks to the Internet Archive |url=https://www.reddit.com/r/CaseyAndAndy/comments/s47x4y/an_index_i_assembled_from_a_post_in_the_nowdead |access-date=15 January 2022 |website=[[Reddit]]}}</ref> ==References== <references/> ==External links== * [http://www.galactanet.com/comic/real.html Galactanet: Andrew Taylor Weir – ''The Real Casey and Andy''] * [http://www.galactanet.com/comic/allstrips.php Index] * {{official website|http://www.caseyandandy.com}} [[Category:2000s webcomics]] [[Category:2001 webcomic debuts]] [[Category:2008 webcomic endings]] [[Category:Science fiction webcomics]] [[Category:American comedy webcomics]] [[Category:Fictional scientists in comics]] [[Category:Works by Andy Weir]] ogyvrtrt40cvudqrmyfo76y2ow73ssj 107904 107903 2026-07-26T11:46:09Z DaSupremo 9 Change category 107904 wikitext text/x-wiki {{Infobox comic strip | title = Casey and Andy | image = | caption = De official logo of de series. | author = [[Andy Weir]] | url = [http://www.galactanet.com/comic/allstrips.php Galactanet] | rss = | atom = | status = Dem fini<ref>{{Cite web |last=Garratt |first=Sheryl |date=26 August 2019 |title=Andy Weir on writing an accidental best-seller |url=https://thecreativelife.net/the-martian-andy-weir-on-writing-an-accidental-best-seller |access-date=26 August 2019 |website=The Creative Life |archive-date=17 September 2021 |archive-url=https://web.archive.org/web/20210917120320/https://thecreativelife.net/the-martian-andy-weir-on-writing-an-accidental-best-seller/ |url-status=live }}</ref> | first = {{br separated entries|28 February 2001|[http://www.galactanet.com/comic/view.php?strip=1 Strip 1]}} | last = {{br separated entries|25 August 2008|[http://www.galactanet.com/comic/view.php?strip=666 Epilogue]}} | syndicate = | publisher = [[LiveJournal]], [[Galactanet]] | genre = [[Action genre|Action]], comedy, [[superhero fiction|superhero]] | rating = | preceded by = | followed by = [[Cheshire Crossing]] }} '''''Casey and Andy''''' (wey dem dey stylize am as '''''Casey & Andy''''', or simply '''''C&A''''') be one [[webcomic]] series wey [[Andy Weir]] wrep den draw. De story dey follow de adventures of two mad scientists (fictional versions of Weir einself den ein best paddie [[Casey Grimm]]) plus dema paddy-dem den oda people wey dem know, like writer [[Jennifer Brozek]]. Dem update de comic three times every week for early 2000s—Monday, Wednesday, den Friday. Most of de time de comic dey use gag-a-comic style, buh e still get long-running storylines den running gags.<ref>{{Cite news |last=Ashley |first=Berty |date=28 October 2022 |title=Quiz — Easy Like Sunday Morning |work=[[The Hindu]] |url=https://www.thehindu.com/books/easy-like-sunday-morning-quiz-berty-ashley/article66039436.ece |access-date=28 October 2022 |quote=[[Andy Weir]] authored a humour [[Webcomic|web comic]] called ''Casey and Andy'', featuring fictionalised ‘mad scientist’ versions of himself and his friends.}}</ref> De comic get strong science den history vibe, plus plenty facts wey come from sources wey no be everybro wey know. E too show say plenty tins wey happen for Weir den Grimm dema real lives resemble wat dey happen insyd de comic. Some strips saf take inspiration from real events wey happen around dat time, like de [[Opportunity mission timeline|''Opportunity'' mission to Mars]], de [[2003 invasion of Iraq]], den de [[2004 United States presidential election]]. Later, dem turn de strip into one [[roleplaying game]] wey dem call ''[[GURPS Casey and Andy]]'' under de [[GURPS]] system. [[David Morgan-Mar]] work on am plus Weir, den [[Steve Jackson Games]] publish one [[PDF]] [[Sourcebook (gaming)|sourcebook]] give am. For 1 May 2006, Weir announce say de strip go end for Strip 666. E talk say e start dey feel too much pressure to make every strip reach de standard wey he want, den he fear say de humor go reduce. He san want get more time make he fit work on ''[[Cheshire Crossing]]'', ein new webcomic project. ''Casey and Andy'' finally end plus ein 666th strip for 25 August 2008. Later, de character Bob appear insyd Weir ein 2017 novel ''[[Artemis (novel)|Artemis]]''.<ref name="AMA">{{Cite web |date=4 December 2017 |title=I am Andy Weir, author of ''The Martian'', and my new book ''Artemis'', out now. AMA! |url=https://www.reddit.com/r/books/comments/7hjh84/i_am_andy_weir_author_of_the_martian_and_my_new/dqrflj2 |access-date=4 December 2017 |website=[[Reddit]] |quote='''u/ManyThingsDeck''': Is the character Bob in ''[[Artemis (novel)|Artemis]]'' an in-joke for your friends who know the story of "And Bob was there too"? '''u/sephalon''': I planned to do that, but later I forgot to put "Bob was there, too" in the book! :( |archive-date=7 January 2022 |archive-url=https://web.archive.org/web/20220107045600/https://www.reddit.com/r/books/comments/7hjh84/i_am_andy_weir_author_of_the_martian_and_my_new/dqrflj2/ |url-status=live }}</ref> For 31 December 2021, dem create one ''Casey and Andy'' subreddit, wey David Morgan-Mar, Casey Grimm, den John Gillman dey oversee, plus Weir ein approval. Dem create am for de social news den discussion website Reddit. Later, de subreddit publish one official crossover comic plus Tredlocity ein science fantasy webcomic ''Val and Isaac'' for January 2022. De comic feature de character Space Dread as de main character. Dem san release one authorised offline-accessible Mega archive of de webcomic.<ref>{{Cite web |date=1 January 2022 |title=A tribute to ''Casey and Andy'', by u/tredlocity (feat. Space Dread) |url=https://www.reddit.com/r/CaseyAndAndy/comments/rt8mm0/a_tribute_to_casey_and_andy_by_utredlocity_feat |access-date=1 January 2022 |website=[[Reddit]]}}</ref><ref>{{Cite web |last=Grimm |first=Casey |author-link=Casey Grimm |date=15 January 2022 |title=''Casey and Andy'' Index — Casey's Webcomics |url=http://gamergeek.org/c_and_a_index.html |access-date=15 January 2022 |website=Gamer Geek |archive-date=21 August 2024 |archive-url=https://web.archive.org/web/20240821192631/http://gamergeek.org/c_and_a_index.html |url-status=live }}</ref><ref>{{Cite web |date=15 January 2022 |title=An index I assembled from a post in the now-dead forum, salvaged thanks to the Internet Archive |url=https://www.reddit.com/r/CaseyAndAndy/comments/s47x4y/an_index_i_assembled_from_a_post_in_the_nowdead |access-date=15 January 2022 |website=[[Reddit]]}}</ref> ==References== <references/> ==External links== * [http://www.galactanet.com/comic/real.html Galactanet: Andrew Taylor Weir – ''The Real Casey and Andy''] * [http://www.galactanet.com/comic/allstrips.php Index] * {{official website|http://www.caseyandandy.com}} [[Category:2000s webcomics]] [[Category:2001 webcomic debuts]] [[Category:2008 webcomic endings]] [[Category:Science fiction webcomics]] [[Category:American comedy webcomics]] [[Category:Fictional scientists insyd comics]] [[Category:Works by Andy Weir]] b8xeldmv4pbdzj1p6zf5usg56wit1ek 0 28884 107892 107890 2026-07-25T17:55:12Z DaSupremo 9 Improve article 107892 wikitext text/x-wiki {{Databox}} '''Chagas disease''', dem sanso know as '''American trypanosomiasis''', be a tropical parasitic disease wey ''Trypanosoma cruzi'' cause. E mostly be spread by insects insyd de subfamily Triatominae, dem know as "kissing bugs". De symptoms change thru out de infection. Insyd de early stage, symptoms be typically either no be present anaa mild den fi include fever, swollen lymph nodes, headaches, anaa swelling at de site of de bite.<ref name=WHO2019>{{cite web|title=Chagas disease (American trypanosomiasis)|url=https://www.who.int/en/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)|date=17 April 2019|website=World Health Organization|access-date=9 March 2020|archive-url=https://web.archive.org/web/20200120210150/https://www.who.int/en/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)|archive-date=20 January 2020}}</ref> After four to eight weeks, untreated individuals enter de chronic phase of disease, wich insyd most cases no dey result in further symptoms.<ref name="Molina20182">{{cite journal |vauthors=Pérez-Molina JA, Molina I |year=2018 |title=Chagas disease |journal=The Lancet |volume=391 |issue=10115 |pages=82–94 |doi=10.1016/S0140-6736(17)31612-4 |issn=0140-6736 |pmid=28673423 |s2cid=4514617}}</ref><ref name="Bern20152">{{cite journal |vauthors=Bern C |date=July 2015 |title=Chagas' disease |journal=N. Engl. J. Med. |type=Review |volume=373 |issue=5 |pages=456–66 |doi=10.1056/NEJMra1410150 |pmid=26222561}}</ref> Up to 45% of people plus chronic infections develop heart disease 10–30 years after de initial illness, wich fi lead to [[heart failure]]. Digestive complications, wey dey include an enlarged esophagus anaa an enlarged colon, sanso fi occur insyd up to 21% of people, den up to 10% of people fi experience nerve damage.<ref name="Molina20182" /> {{nowrap|''T. cruzi''}} commonly be spread to humans den oda mammals by de kissing bug's bite wound den infected feces.<ref name=CDC>{{cite web |publisher=Centers for Disease Control (CDC) |url=https://www.cdc.gov/dpdx/trypanosomiasisAmerican/ |title=DPDx&nbsp;– Trypanosomiasis, American. Fact Sheet |date=30 April 2019| access-date=10 March 2020 |url-status=live |archive-url=https://web.archive.org/web/20190905010437/https://www.cdc.gov/dpdx/trypanosomiasisAmerican/ |archive-date=5 September 2019}}</ref> De disease sanso fi be spread thru blood transfusion, organ transplantation, consuming food anaa drink contaminated plus de parasites, den vertical transmission (from a mommie to ein baby).<ref name=WHO2019/> Diagnosis of early disease be by finding de parasite insyd de blood using a microscope anaa detecting ein DNA by polymerase chain reaction.<ref name="Bern20152" /> Chronic disease be diagnosed by finding antibodies for {{nowrap|''T. cruzi''}} insyd de blood.<ref name=Gua2019>{{cite journal |vauthors= Guarner J |title=Chagas disease as example of a reemerging parasite |journal=Seminars in Diagnostic Pathology |date=May 2019 |volume=36 |issue=3 |pages=164–9 |doi=10.1053/j.semdp.2019.04.008 |pmid=31006555|doi-access=free }}</ref> Prevention dey focus on eliminating kissing bugs den avoiding dema bites.<ref name=WHO2019/> Dis fi involve de use of insecticides anaa bed-nets.<ref>{{cite web|title=Prevention of Chagas disease|url=https://www.who.int/chagas/disease/prevention/en/|website=World Health Organization|access-date=24 February 2018|archive-url=https://web.archive.org/web/20180211034545/http://www.who.int/chagas/disease/prevention/en/|archive-date=11 February 2018}}</ref> Oda preventive efforts dey include screening blood used for transfusions. Early infections be treatable plus de medications benznidazole anaa nifurtimox, wich usually cure de disease if given shortly after de person be infected, buh cam be less effective de longer a person get Chagas disease. Wen dem use insyd chronic disease, medication fi delay anaa prevent de development of end-stage symptoms. Benznidazole den nifurtimox often cause side effects, wey dey include skin disorders, digestive system irritation, den neurological symptoms, wich fi result in treatment being discontinued.<ref name="Molina20182" /><ref name=Santi2022>{{cite journal |vauthors= Santi AM, Murta SM|title=Antioxidant defence system as a rational target for Chagas disease and Leishmaniasis chemotherapy |journal=[[Memórias do Instituto Oswaldo Cruz]] |date=2022 |volume= 117|article-number=e210401|doi=10.1590/0074-02760210401|pmid= 35239945|pmc=8896756 |doi-access=free}}</ref> New drugs for Chagas disease be under development,<ref name=Porta2023>{{cite journal |vauthors=Porta EO, Kalesh K, Steel PG |title=Navigating drug repurposing for Chagas disease: advances, challenges, and opportunities |journal=Front Pharmacol |volume=14 |issue= |article-number=1233253 |date=2023 |pmid=37576826 |pmc=10416112 |doi=10.3389/fphar.2023.1233253 |doi-access=free |url=}}</ref> den while experimental vaccines be studied insyd animal models,<ref name="Rios20192">{{cite journal |vauthors=Rios LE, Vázquez-Chagoyán JC, Pacheco AO, Zago MP, Garg NJ |year=2019 |title=Immunity and vaccine development efforts against Trypanosoma cruzi |journal=Acta Tropica |volume=200 |doi=10.1016/j.actatropica.2019.105168 |issn=0001-706X |pmc=7409534 |pmid=31513763 |doi-access=free |article-number=105168}}</ref><ref name="Vermelho20192">{{cite journal |vauthors=Vermelho AB, Rodrigues GC, Supuran CT |year=2019 |title=Why hasn't there been more progress in new Chagas disease drug discovery? |journal=Expert Opinion on Drug Discovery |volume=15 |issue=2 |pages=145–158 |doi=10.1080/17460441.2020.1681394 |issn=1746-0441 |pmid=31670987 |s2cid=207815975}}</ref> dem no develop a human vaccine develop. == References == <references /> == External links == [[Category:Translated from MDWiki]] r3qythdh6es6x4yc8lqd4q42s08ll5a 107893 107892 2026-07-25T17:59:24Z DaSupremo 9 Improve article 107893 wikitext text/x-wiki {{Databox}} '''Chagas disease''', dem sanso know as '''American trypanosomiasis''', be a tropical parasitic disease wey ''Trypanosoma cruzi'' cause. E mostly be spread by insects insyd de subfamily Triatominae, dem know as "kissing bugs". De symptoms change thru out de infection. Insyd de early stage, symptoms be typically either no be present anaa mild den fi include fever, swollen lymph nodes, headaches, anaa swelling at de site of de bite.<ref name=WHO2019>{{cite web|title=Chagas disease (American trypanosomiasis)|url=https://www.who.int/en/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)|date=17 April 2019|website=World Health Organization|access-date=9 March 2020|archive-url=https://web.archive.org/web/20200120210150/https://www.who.int/en/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)|archive-date=20 January 2020}}</ref> After four to eight weeks, untreated individuals enter de chronic phase of disease, wich insyd most cases no dey result in further symptoms.<ref name="Molina20182">{{cite journal |vauthors=Pérez-Molina JA, Molina I |year=2018 |title=Chagas disease |journal=The Lancet |volume=391 |issue=10115 |pages=82–94 |doi=10.1016/S0140-6736(17)31612-4 |issn=0140-6736 |pmid=28673423 |s2cid=4514617}}</ref><ref name="Bern20152">{{cite journal |vauthors=Bern C |date=July 2015 |title=Chagas' disease |journal=N. Engl. J. Med. |type=Review |volume=373 |issue=5 |pages=456–66 |doi=10.1056/NEJMra1410150 |pmid=26222561}}</ref> Up to 45% of people plus chronic infections develop heart disease 10–30 years after de initial illness, wich fi lead to [[heart failure]]. Digestive complications, wey dey include an enlarged esophagus anaa an enlarged colon, sanso fi occur insyd up to 21% of people, den up to 10% of people fi experience nerve damage.<ref name="Molina20182" /> {{nowrap|''T. cruzi''}} commonly be spread to humans den oda mammals by de kissing bug's bite wound den infected feces.<ref name=CDC>{{cite web |publisher=Centers for Disease Control (CDC) |url=https://www.cdc.gov/dpdx/trypanosomiasisAmerican/ |title=DPDx&nbsp;– Trypanosomiasis, American. Fact Sheet |date=30 April 2019| access-date=10 March 2020 |url-status=live |archive-url=https://web.archive.org/web/20190905010437/https://www.cdc.gov/dpdx/trypanosomiasisAmerican/ |archive-date=5 September 2019}}</ref> De disease sanso fi be spread thru blood transfusion, organ transplantation, consuming food anaa drink contaminated plus de parasites, den vertical transmission (from a mommie to ein baby).<ref name=WHO2019/> Diagnosis of early disease be by finding de parasite insyd de blood using a microscope anaa detecting ein DNA by polymerase chain reaction.<ref name="Bern20152" /> Chronic disease be diagnosed by finding antibodies for {{nowrap|''T. cruzi''}} insyd de blood.<ref name=Gua2019>{{cite journal |vauthors= Guarner J |title=Chagas disease as example of a reemerging parasite |journal=Seminars in Diagnostic Pathology |date=May 2019 |volume=36 |issue=3 |pages=164–9 |doi=10.1053/j.semdp.2019.04.008 |pmid=31006555|doi-access=free }}</ref> Prevention dey focus on eliminating kissing bugs den avoiding dema bites.<ref name=WHO2019/> Dis fi involve de use of insecticides anaa bed-nets.<ref>{{cite web|title=Prevention of Chagas disease|url=https://www.who.int/chagas/disease/prevention/en/|website=World Health Organization|access-date=24 February 2018|archive-url=https://web.archive.org/web/20180211034545/http://www.who.int/chagas/disease/prevention/en/|archive-date=11 February 2018}}</ref> Oda preventive efforts dey include screening blood used for transfusions. Early infections be treatable plus de medications benznidazole anaa nifurtimox, wich usually cure de disease if given shortly after de person be infected, buh cam be less effective de longer a person get Chagas disease. Wen dem use insyd chronic disease, medication fi delay anaa prevent de development of end-stage symptoms. Benznidazole den nifurtimox often cause side effects, wey dey include skin disorders, digestive system irritation, den neurological symptoms, wich fi result in treatment being discontinued.<ref name="Molina20182" /><ref name=Santi2022>{{cite journal |vauthors= Santi AM, Murta SM|title=Antioxidant defence system as a rational target for Chagas disease and Leishmaniasis chemotherapy |journal=[[Memórias do Instituto Oswaldo Cruz]] |date=2022 |volume= 117|article-number=e210401|doi=10.1590/0074-02760210401|pmid= 35239945|pmc=8896756 |doi-access=free}}</ref> New drugs for Chagas disease be under development,<ref name=Porta2023>{{cite journal |vauthors=Porta EO, Kalesh K, Steel PG |title=Navigating drug repurposing for Chagas disease: advances, challenges, and opportunities |journal=Front Pharmacol |volume=14 |issue= |article-number=1233253 |date=2023 |pmid=37576826 |pmc=10416112 |doi=10.3389/fphar.2023.1233253 |doi-access=free |url=}}</ref> den while experimental vaccines be studied insyd animal models,<ref name="Rios20192">{{cite journal |vauthors=Rios LE, Vázquez-Chagoyán JC, Pacheco AO, Zago MP, Garg NJ |year=2019 |title=Immunity and vaccine development efforts against Trypanosoma cruzi |journal=Acta Tropica |volume=200 |doi=10.1016/j.actatropica.2019.105168 |issn=0001-706X |pmc=7409534 |pmid=31513763 |doi-access=free |article-number=105168}}</ref><ref name="Vermelho20192">{{cite journal |vauthors=Vermelho AB, Rodrigues GC, Supuran CT |year=2019 |title=Why hasn't there been more progress in new Chagas disease drug discovery? |journal=Expert Opinion on Drug Discovery |volume=15 |issue=2 |pages=145–158 |doi=10.1080/17460441.2020.1681394 |issn=1746-0441 |pmid=31670987 |s2cid=207815975}}</ref> dem no develop a human vaccine develop. E be estimated say 6.5 million people, mostly insyd [[Mexico]], Central America den South America, get Chagas disease as of 2019,<ref name="WHO2019"/> wey dey result in approximately 9,490 annual deaths. Most people plus de disease be poor,<ref name=Rassi2012>{{cite journal|vauthors=Rassi Jr A, Rassi A, Marcondes de Rezende J|title=American trypanosomiasis (Chagas disease)|journal=Infectious Disease Clinics of North America|date=June 2012|volume=26|issue=2|pages=275–91|pmid=22632639|doi=10.1016/j.idc.2012.03.002|s2cid=34941921 }}</ref> wey most no realize dem be infected.<ref>{{cite book|editor= Capinera JL |title=Encyclopedia of entomology |year=2008|publisher=Springer|location=Dordrecht|isbn=978-1-4020-6242-1|page=[https://books.google.com/books?id=i9ITMiiohVQC&pg=PA824 824] |edition=2nd}}</ref> Large-scale population migrations carry Chagas disease to new regions, wich include de [[United States]] den chaw European countries.<ref name=WHO2019/> De disease dey affect more dan 150 types of animals.<ref name=Rassi2010>{{cite journal |vauthors=Rassi A, Rassi A, Marin-Neto JA |title=Chagas disease |journal=Lancet |volume=375 |issue=9723 |pages=1388–402 |date=April 2010 |pmid=20399979 |doi=10.1016/S0140-6736(10)60061-X|s2cid=5068417 }}</ref> From 2000–2018, na dem report 29 confirmed locally-acquired cases of Chagas disease insyd eight US states, wey dey lead to calls to reclassify Chagas as endemic to de US. == References == <references /> == External links == [[Category:Translated from MDWiki]] s915n15czcwoq01j0pz0f13iaqzb1l2 107894 107893 2026-07-25T18:01:51Z DaSupremo 9 Improve article 107894 wikitext text/x-wiki {{Databox}} '''Chagas disease''', dem sanso know as '''American trypanosomiasis''', be a tropical parasitic disease wey ''Trypanosoma cruzi'' cause. E mostly be spread by insects insyd de subfamily Triatominae, dem know as "kissing bugs". De symptoms change thru out de infection. Insyd de early stage, symptoms be typically either no be present anaa mild den fi include fever, swollen lymph nodes, headaches, anaa swelling at de site of de bite.<ref name=WHO2019>{{cite web|title=Chagas disease (American trypanosomiasis)|url=https://www.who.int/en/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)|date=17 April 2019|website=World Health Organization|access-date=9 March 2020|archive-url=https://web.archive.org/web/20200120210150/https://www.who.int/en/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)|archive-date=20 January 2020}}</ref> After four to eight weeks, untreated individuals enter de chronic phase of disease, wich insyd most cases no dey result in further symptoms.<ref name="Molina20182">{{cite journal |vauthors=Pérez-Molina JA, Molina I |year=2018 |title=Chagas disease |journal=The Lancet |volume=391 |issue=10115 |pages=82–94 |doi=10.1016/S0140-6736(17)31612-4 |issn=0140-6736 |pmid=28673423 |s2cid=4514617}}</ref><ref name="Bern20152">{{cite journal |vauthors=Bern C |date=July 2015 |title=Chagas' disease |journal=N. Engl. J. Med. |type=Review |volume=373 |issue=5 |pages=456–66 |doi=10.1056/NEJMra1410150 |pmid=26222561}}</ref> Up to 45% of people plus chronic infections develop heart disease 10–30 years after de initial illness, wich fi lead to [[heart failure]]. Digestive complications, wey dey include an enlarged esophagus anaa an enlarged colon, sanso fi occur insyd up to 21% of people, den up to 10% of people fi experience nerve damage.<ref name="Molina20182" /> {{nowrap|''T. cruzi''}} commonly be spread to humans den oda mammals by de kissing bug's bite wound den infected feces.<ref name=CDC>{{cite web |publisher=Centers for Disease Control (CDC) |url=https://www.cdc.gov/dpdx/trypanosomiasisAmerican/ |title=DPDx&nbsp;– Trypanosomiasis, American. Fact Sheet |date=30 April 2019| access-date=10 March 2020 |url-status=live |archive-url=https://web.archive.org/web/20190905010437/https://www.cdc.gov/dpdx/trypanosomiasisAmerican/ |archive-date=5 September 2019}}</ref> De disease sanso fi be spread thru blood transfusion, organ transplantation, consuming food anaa drink contaminated plus de parasites, den vertical transmission (from a mommie to ein baby).<ref name=WHO2019/> Diagnosis of early disease be by finding de parasite insyd de blood using a microscope anaa detecting ein DNA by polymerase chain reaction.<ref name="Bern20152" /> Chronic disease be diagnosed by finding antibodies for {{nowrap|''T. cruzi''}} insyd de blood.<ref name=Gua2019>{{cite journal |vauthors= Guarner J |title=Chagas disease as example of a reemerging parasite |journal=Seminars in Diagnostic Pathology |date=May 2019 |volume=36 |issue=3 |pages=164–9 |doi=10.1053/j.semdp.2019.04.008 |pmid=31006555|doi-access=free }}</ref> Prevention dey focus on eliminating kissing bugs den avoiding dema bites.<ref name=WHO2019/> Dis fi involve de use of insecticides anaa bed-nets.<ref>{{cite web|title=Prevention of Chagas disease|url=https://www.who.int/chagas/disease/prevention/en/|website=World Health Organization|access-date=24 February 2018|archive-url=https://web.archive.org/web/20180211034545/http://www.who.int/chagas/disease/prevention/en/|archive-date=11 February 2018}}</ref> Oda preventive efforts dey include screening blood used for transfusions. Early infections be treatable plus de medications benznidazole anaa nifurtimox, wich usually cure de disease if given shortly after de person be infected, buh cam be less effective de longer a person get Chagas disease. Wen dem use insyd chronic disease, medication fi delay anaa prevent de development of end-stage symptoms. Benznidazole den nifurtimox often cause side effects, wey dey include skin disorders, digestive system irritation, den neurological symptoms, wich fi result in treatment being discontinued.<ref name="Molina20182" /><ref name=Santi2022>{{cite journal |vauthors= Santi AM, Murta SM|title=Antioxidant defence system as a rational target for Chagas disease and Leishmaniasis chemotherapy |journal=[[Memórias do Instituto Oswaldo Cruz]] |date=2022 |volume= 117|article-number=e210401|doi=10.1590/0074-02760210401|pmid= 35239945|pmc=8896756 |doi-access=free}}</ref> New drugs for Chagas disease be under development,<ref name=Porta2023>{{cite journal |vauthors=Porta EO, Kalesh K, Steel PG |title=Navigating drug repurposing for Chagas disease: advances, challenges, and opportunities |journal=Front Pharmacol |volume=14 |issue= |article-number=1233253 |date=2023 |pmid=37576826 |pmc=10416112 |doi=10.3389/fphar.2023.1233253 |doi-access=free |url=}}</ref> den while experimental vaccines be studied insyd animal models,<ref name="Rios20192">{{cite journal |vauthors=Rios LE, Vázquez-Chagoyán JC, Pacheco AO, Zago MP, Garg NJ |year=2019 |title=Immunity and vaccine development efforts against Trypanosoma cruzi |journal=Acta Tropica |volume=200 |doi=10.1016/j.actatropica.2019.105168 |issn=0001-706X |pmc=7409534 |pmid=31513763 |doi-access=free |article-number=105168}}</ref><ref name="Vermelho20192">{{cite journal |vauthors=Vermelho AB, Rodrigues GC, Supuran CT |year=2019 |title=Why hasn't there been more progress in new Chagas disease drug discovery? |journal=Expert Opinion on Drug Discovery |volume=15 |issue=2 |pages=145–158 |doi=10.1080/17460441.2020.1681394 |issn=1746-0441 |pmid=31670987 |s2cid=207815975}}</ref> dem no develop a human vaccine develop. E be estimated say 6.5 million people, mostly insyd [[Mexico]], Central America den South America, get Chagas disease as of 2019,<ref name="WHO2019"/><ref name="GBD2019">{{cite web |date=2020 |title=Global Health Metrics: Chagas disease—Level 3 cause |url=https://www.thelancet.com/pb-assets/Lancet/gbd/summaries/diseases/chagas-disease.pdf |url-status=live |archive-url=https://web.archive.org/web/20220318033609/https://www.thelancet.com/pb-assets/Lancet/gbd/summaries/diseases/chagas-disease.pdf |archive-date=18 March 2022 |work=[[The Lancet]]}}</ref> wey dey result in approximately 9,490 annual deaths.<ref name="GBD2019" /> Most people plus de disease be poor,<ref name=Rassi2012>{{cite journal|vauthors=Rassi Jr A, Rassi A, Marcondes de Rezende J|title=American trypanosomiasis (Chagas disease)|journal=Infectious Disease Clinics of North America|date=June 2012|volume=26|issue=2|pages=275–91|pmid=22632639|doi=10.1016/j.idc.2012.03.002|s2cid=34941921 }}</ref> wey most no realize dem be infected.<ref>{{cite book|editor= Capinera JL |title=Encyclopedia of entomology |year=2008|publisher=Springer|location=Dordrecht|isbn=978-1-4020-6242-1|page=[https://books.google.com/books?id=i9ITMiiohVQC&pg=PA824 824] |edition=2nd}}</ref> Large-scale population migrations carry Chagas disease to new regions, wich include de [[United States]] den chaw European countries.<ref name=WHO2019/> De disease dey affect more dan 150 types of animals.<ref name=Rassi2010>{{cite journal |vauthors=Rassi A, Rassi A, Marin-Neto JA |title=Chagas disease |journal=Lancet |volume=375 |issue=9723 |pages=1388–402 |date=April 2010 |pmid=20399979 |doi=10.1016/S0140-6736(10)60061-X|s2cid=5068417 }}</ref> From 2000–2018, na dem report 29 confirmed locally-acquired cases of Chagas disease insyd eight US states, wey dey lead to calls to reclassify Chagas as endemic to de US.<ref name="Beatty">{{cite journal |last1=Beatty |first1=Norman L. |last2=Hamer |first2=Gabriel L. |last3=Moreno-Peniche |first3=Bernardo |last4=Mayes |first4=Bonny |last5=Hamer |first5=Sarah A. |date=September 2025 |title=Chagas Disease, an Endemic Disease in the United States |journal=Emerging Infectious Diseases |volume=31 |issue=9 |doi=10.3201/eid3109.241700 |pmc=12407112 |doi-access=free}}</ref> De disease first be described insyd 1909 by Brazilian physician Carlos Chagas, after whom dem name.<ref name=WHO2019/> Chagas disease be classified as a neglected tropical disease.<ref name=NTD2017>{{cite web|title=Neglected Tropical Diseases |url=https://www.cdc.gov/globalhealth/ntd/diseases/index.html|website=cdc.gov|access-date=28 November 2014|date=6 June 2011|url-status=live|archive-url= https://web.archive.org/web/20141204084219/http://www.cdc.gov/globalhealth/ntd/diseases/index.html |archive-date= 4 December 2014}}</ref> == References == <references /> == External links == [[Category:Translated from MDWiki]] idyz6qcqep8kuz62ta1sqdxz1bsw577 107895 107894 2026-07-25T18:04:42Z DaSupremo 9 Improve article 107895 wikitext text/x-wiki {{Databox}} '''Chagas disease''', dem sanso know as '''American trypanosomiasis''', be a tropical parasitic disease wey ''Trypanosoma cruzi'' cause. E mostly be spread by insects insyd de subfamily Triatominae, dem know as "kissing bugs". De symptoms change thru out de infection. Insyd de early stage, symptoms be typically either no be present anaa mild den fi include fever, swollen lymph nodes, headaches, anaa swelling at de site of de bite.<ref name=WHO2019>{{cite web|title=Chagas disease (American trypanosomiasis)|url=https://www.who.int/en/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)|date=17 April 2019|website=World Health Organization|access-date=9 March 2020|archive-url=https://web.archive.org/web/20200120210150/https://www.who.int/en/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)|archive-date=20 January 2020}}</ref> After four to eight weeks, untreated individuals enter de chronic phase of disease, wich insyd most cases no dey result in further symptoms.<ref name="Molina20182">{{cite journal |vauthors=Pérez-Molina JA, Molina I |year=2018 |title=Chagas disease |journal=The Lancet |volume=391 |issue=10115 |pages=82–94 |doi=10.1016/S0140-6736(17)31612-4 |issn=0140-6736 |pmid=28673423 |s2cid=4514617}}</ref><ref name="Bern20152">{{cite journal |vauthors=Bern C |date=July 2015 |title=Chagas' disease |journal=N. Engl. J. Med. |type=Review |volume=373 |issue=5 |pages=456–66 |doi=10.1056/NEJMra1410150 |pmid=26222561}}</ref> Up to 45% of people plus chronic infections develop heart disease 10–30 years after de initial illness, wich fi lead to [[heart failure]]. Digestive complications, wey dey include an enlarged esophagus anaa an enlarged colon, sanso fi occur insyd up to 21% of people, den up to 10% of people fi experience nerve damage.<ref name="Molina20182" /> {{nowrap|''T. cruzi''}} commonly be spread to humans den oda mammals by de kissing bug's bite wound den infected feces.<ref name=CDC>{{cite web |publisher=Centers for Disease Control (CDC) |url=https://www.cdc.gov/dpdx/trypanosomiasisAmerican/ |title=DPDx&nbsp;– Trypanosomiasis, American. Fact Sheet |date=30 April 2019| access-date=10 March 2020 |url-status=live |archive-url=https://web.archive.org/web/20190905010437/https://www.cdc.gov/dpdx/trypanosomiasisAmerican/ |archive-date=5 September 2019}}</ref> De disease sanso fi be spread thru blood transfusion, organ transplantation, consuming food anaa drink contaminated plus de parasites, den vertical transmission (from a mommie to ein baby).<ref name=WHO2019/> Diagnosis of early disease be by finding de parasite insyd de blood using a microscope anaa detecting ein DNA by polymerase chain reaction.<ref name="Bern20152" /> Chronic disease be diagnosed by finding antibodies for {{nowrap|''T. cruzi''}} insyd de blood.<ref name=Gua2019>{{cite journal |vauthors= Guarner J |title=Chagas disease as example of a reemerging parasite |journal=Seminars in Diagnostic Pathology |date=May 2019 |volume=36 |issue=3 |pages=164–9 |doi=10.1053/j.semdp.2019.04.008 |pmid=31006555|doi-access=free }}</ref> Prevention dey focus on eliminating kissing bugs den avoiding dema bites.<ref name=WHO2019/> Dis fi involve de use of insecticides anaa bed-nets.<ref>{{cite web|title=Prevention of Chagas disease|url=https://www.who.int/chagas/disease/prevention/en/|website=World Health Organization|access-date=24 February 2018|archive-url=https://web.archive.org/web/20180211034545/http://www.who.int/chagas/disease/prevention/en/|archive-date=11 February 2018}}</ref> Oda preventive efforts dey include screening blood used for transfusions. Early infections be treatable plus de medications benznidazole anaa nifurtimox, wich usually cure de disease if given shortly after de person be infected, buh cam be less effective de longer a person get Chagas disease. Wen dem use insyd chronic disease, medication fi delay anaa prevent de development of end-stage symptoms. Benznidazole den nifurtimox often cause side effects, wey dey include skin disorders, digestive system irritation, den neurological symptoms, wich fi result in treatment being discontinued.<ref name="Molina20182" /><ref name=Santi2022>{{cite journal |vauthors= Santi AM, Murta SM|title=Antioxidant defence system as a rational target for Chagas disease and Leishmaniasis chemotherapy |journal=[[Memórias do Instituto Oswaldo Cruz]] |date=2022 |volume= 117|article-number=e210401|doi=10.1590/0074-02760210401|pmid= 35239945|pmc=8896756 |doi-access=free}}</ref> New drugs for Chagas disease be under development,<ref name=Porta2023>{{cite journal |vauthors=Porta EO, Kalesh K, Steel PG |title=Navigating drug repurposing for Chagas disease: advances, challenges, and opportunities |journal=Front Pharmacol |volume=14 |issue= |article-number=1233253 |date=2023 |pmid=37576826 |pmc=10416112 |doi=10.3389/fphar.2023.1233253 |doi-access=free |url=}}</ref> den while experimental vaccines be studied insyd animal models,<ref name="Rios20192">{{cite journal |vauthors=Rios LE, Vázquez-Chagoyán JC, Pacheco AO, Zago MP, Garg NJ |year=2019 |title=Immunity and vaccine development efforts against Trypanosoma cruzi |journal=Acta Tropica |volume=200 |doi=10.1016/j.actatropica.2019.105168 |issn=0001-706X |pmc=7409534 |pmid=31513763 |doi-access=free |article-number=105168}}</ref><ref name="Vermelho20192">{{cite journal |vauthors=Vermelho AB, Rodrigues GC, Supuran CT |year=2019 |title=Why hasn't there been more progress in new Chagas disease drug discovery? |journal=Expert Opinion on Drug Discovery |volume=15 |issue=2 |pages=145–158 |doi=10.1080/17460441.2020.1681394 |issn=1746-0441 |pmid=31670987 |s2cid=207815975}}</ref> dem no develop a human vaccine develop. E be estimated say 6.5 million people, mostly insyd [[Mexico]], Central America den South America, get Chagas disease as of 2019,<ref name="WHO2019"/><ref name="GBD2019">{{cite web |date=2020 |title=Global Health Metrics: Chagas disease—Level 3 cause |url=https://www.thelancet.com/pb-assets/Lancet/gbd/summaries/diseases/chagas-disease.pdf |url-status=live |archive-url=https://web.archive.org/web/20220318033609/https://www.thelancet.com/pb-assets/Lancet/gbd/summaries/diseases/chagas-disease.pdf |archive-date=18 March 2022 |work=[[The Lancet]]}}</ref> wey dey result in approximately 9,490 annual deaths.<ref name="GBD2019" /> Most people plus de disease be poor,<ref name=Rassi2012>{{cite journal|vauthors=Rassi Jr A, Rassi A, Marcondes de Rezende J|title=American trypanosomiasis (Chagas disease)|journal=Infectious Disease Clinics of North America|date=June 2012|volume=26|issue=2|pages=275–91|pmid=22632639|doi=10.1016/j.idc.2012.03.002|s2cid=34941921 }}</ref> wey most no realize dem be infected.<ref>{{cite book|editor= Capinera JL |title=Encyclopedia of entomology |year=2008|publisher=Springer|location=Dordrecht|isbn=978-1-4020-6242-1|page=[https://books.google.com/books?id=i9ITMiiohVQC&pg=PA824 824] |edition=2nd}}</ref> Large-scale population migrations carry Chagas disease to new regions, wich include de [[United States]] den chaw European countries.<ref name=WHO2019/> De disease dey affect more dan 150 types of animals.<ref name=Rassi2010>{{cite journal |vauthors=Rassi A, Rassi A, Marin-Neto JA |title=Chagas disease |journal=Lancet |volume=375 |issue=9723 |pages=1388–402 |date=April 2010 |pmid=20399979 |doi=10.1016/S0140-6736(10)60061-X|s2cid=5068417 }}</ref> From 2000–2018, na dem report 29 confirmed locally-acquired cases of Chagas disease insyd eight US states, wey dey lead to calls to reclassify Chagas as endemic to de US.<ref name="Beatty">{{cite journal |last1=Beatty |first1=Norman L. |last2=Hamer |first2=Gabriel L. |last3=Moreno-Peniche |first3=Bernardo |last4=Mayes |first4=Bonny |last5=Hamer |first5=Sarah A. |date=September 2025 |title=Chagas Disease, an Endemic Disease in the United States |journal=Emerging Infectious Diseases |volume=31 |issue=9 |doi=10.3201/eid3109.241700 |pmc=12407112 |doi-access=free}}</ref> De disease first be described insyd 1909 by Brazilian physician Carlos Chagas, after whom dem name.<ref name=WHO2019/> Chagas disease be classified as a neglected tropical disease.<ref name=NTD2017>{{cite web|title=Neglected Tropical Diseases |url=https://www.cdc.gov/globalhealth/ntd/diseases/index.html|website=cdc.gov|access-date=28 November 2014|date=6 June 2011|url-status=live|archive-url= https://web.archive.org/web/20141204084219/http://www.cdc.gov/globalhealth/ntd/diseases/index.html |archive-date= 4 December 2014}}</ref> == References == <references /> == External links == {{Commons}} * [https://www.cdc.gov/chagas/ Chagas information] at the U.S. Centers for Disease Control * [https://www.dndi.org/?s=chagas Chagas information] from the Drugs for Neglected Diseases initiative * [https://www.iamat.org/risks/chagas-disease Chagas disease information] for travellers from the International Association for Medical Assistance to Travellers {{Authority control}} {{DEFAULTSORT:Chagas Disease}} [[Category:Chagas disease| ]] [[Category:Diseases dem name after discoverers]] [[Category:Parasitic infestations, stings, den bites of de skin]] [[Category:Insect-borne diseases]] [[Category:Protozoal diseases]] [[Category:Tropical diseases]] [[Category:Zoonoses]] [[Category:Translated from MDWiki]] fdeydtm980i8c5hphwyd2jpwa2v87qa 14 28912 107896 2026-07-25T18:05:17Z DaSupremo 9 Fresh category 107896 wikitext text/x-wiki phoiac9h4m842xq45sp7s6u21eteeq1 0 28913 107897 2026-07-25T18:06:50Z DaSupremo 9 Created by translating the page [[:mdwiki:Special:Redirect/revision/1500348|Aneurysm]] to:gpe #mdwikicx 107897 wikitext text/x-wiki [[Category:Translated from MDWiki]] r0gf7axtnvt68k0p85plnlehx64o08u 107898 107897 2026-07-25T20:01:30Z DaSupremo 9 Improve article 107898 wikitext text/x-wiki {{Databox}} An '''aneurysm''' be an outward [[:wikt:bulge|bulging]], dem liken to a bubble anaa balloon, wey a localized, abnormal, weak spot on a blood vessel wall cause.<ref>{{cite web|url=https://www.nhlbi.nih.gov/health-topics/aneurysm|archive-url=https://web.archive.org/web/20171222114406/https://www.nhlbi.nih.gov/health-topics/aneurysm|archive-date=22 December 2017|title=Aneurysms|website=Society of NeuroInterventional Surgery|access-date=23 February 2018}}</ref> Aneurysms fi be a result of a hereditary condition anaa an acquired disease. Aneurysms sanso fi be a [[wikt:Special:Search/nidus|nidus]] (starting point) for clot formation (thrombosis) den embolization. As an aneurysm dey increase in size, de risk of rupture dey increase, wich fi lead to uncontrolled bleeding.<ref>{{cite journal | vauthors = Cronenwett JL, Murphy TF, Zelenock GB, Whitehouse WM, Lindenauer SM, Graham LM, Quint LE, Silver TM, Stanley JC | title = Actuarial analysis of variables associated with rupture of small abdominal aortic aneurysms | journal = Surgery | volume = 98 | issue = 3 | pages = 472–83 | date = September 1985 | pmid = 3898453 }}</ref> Although dem fi occur insyd any blood vessel, particularly lethal examples include aneurysms of de circle of Willis insyd de brain, aortic aneurysms wey dey affect de thoracic aorta, den abdominal aortic aneurysms. Aneurysms fi arise insyd de heart following a heart attack, wey dey include both ventricular den atrial septal aneurysms. Der be congenital atrial septal aneurysms, a rare heart defect. == References == [[Category:Translated from MDWiki]] <references /> == External links == 84sp8boa0bp0ydbers17uqp2eolx19j 107899 107898 2026-07-25T23:24:04Z DaSupremo 9 /* Notable cases */ Improve article 107899 wikitext text/x-wiki {{Databox}} An '''aneurysm''' be an outward [[:wikt:bulge|bulging]], dem liken to a bubble anaa balloon, wey a localized, abnormal, weak spot on a blood vessel wall cause.<ref>{{cite web|url=https://www.nhlbi.nih.gov/health-topics/aneurysm|archive-url=https://web.archive.org/web/20171222114406/https://www.nhlbi.nih.gov/health-topics/aneurysm|archive-date=22 December 2017|title=Aneurysms|website=Society of NeuroInterventional Surgery|access-date=23 February 2018}}</ref> Aneurysms fi be a result of a hereditary condition anaa an acquired disease. Aneurysms sanso fi be a [[wikt:Special:Search/nidus|nidus]] (starting point) for clot formation (thrombosis) den embolization. As an aneurysm dey increase in size, de risk of rupture dey increase, wich fi lead to uncontrolled bleeding.<ref>{{cite journal | vauthors = Cronenwett JL, Murphy TF, Zelenock GB, Whitehouse WM, Lindenauer SM, Graham LM, Quint LE, Silver TM, Stanley JC | title = Actuarial analysis of variables associated with rupture of small abdominal aortic aneurysms | journal = Surgery | volume = 98 | issue = 3 | pages = 472–83 | date = September 1985 | pmid = 3898453 }}</ref> Although dem fi occur insyd any blood vessel, particularly lethal examples include aneurysms of de circle of Willis insyd de brain, aortic aneurysms wey dey affect de thoracic aorta, den abdominal aortic aneurysms. Aneurysms fi arise insyd de heart following a heart attack, wey dey include both ventricular den atrial septal aneurysms. Der be congenital atrial septal aneurysms, a rare heart defect. ==Notable cases== <!-- This should only include either extremely notable individuals who died from routine aneurysms (e.g., Albert Einstein) or otherwise notable individuals who died from notable or rare aneurysms. Please do not include every instance of a notable individual who died from an aneurysm. --> * Senator Joe Biden. * Lucille Ball.<ref name="Lucille Ball dies">{{cite news |last=Ball |first=Lucille | name-list-style = vanc |title=Lucy dies |url=https://www.chicagotribune.com/1989/04/27/tvs-lucille-ball-dies-of-heart-failure-at-77/ |newspaper=[[Chicago Tribune]] |date=27 April 1989 |access-date=12 May 2013}}</ref><ref>{{cite web|url=http://www.highbeam.com/doc/1P2-1187461.html|archive-url=https://web.archive.org/web/20121106080946/http://www.highbeam.com/doc/1P2-1187461.html|archive-date=6 November 2012|title=Article: Lucille Ball, Pioneer of Television Comedy, Dies at 77|date=27 April 1989 |access-date=31 August 2009}}</ref><ref name="Ball Dies of Aorta Failure">{{cite news|last=Ball|first=Lucille| name-list-style = vanc |title=Ball dies of ruptured aorta|url=https://www.latimes.com/archives/la-xpm-1989-04-27-mn-1618-story.html |newspaper=Los Angeles Times |date=27 April 1989 |access-date=12 May 2013}}</ref> * Laura Branigan * David Cone * Davie Cooper * John Olerud * Albert Einstein<ref>{{cite web | title = Dr. Albert Einstein Dies in Sleep at 76; World Mourns Loss of Great Scientist | url = https://www.nytimes.com/learning/general/onthisday/bday/0314.html | date = 19 April 1955 | work = The New York Times }}</ref> * Thomas Mikal Ford * Charles de Gaulle.<ref>{{Cite web |last=Larousse |first=Éditions |title=Archive Larousse : Journal de l'année Édition 1971 - dossier - Dossier Charles de Gaulle 1890-1970, Un jour comme les autres |url=https://www.larousse.fr/archives/journaux_annee/1971/8/dossier_charles_de_gaulle_1890-1970 |access-date=2026-04-19 |website=Larousse.fr |language=fr}}</ref> * Richard Holbrooke<ref>{{cite web | title = US Diplomat Holbrooke dies after tearing arota | website = [[NBC News]] | date = 14 December 2010 | url = https://www.nbcnews.com/id/wbna40649624 }}</ref> * Édith Piaf * Stuart Sutcliffe<ref>{{cite web | title = Stuart Sutcliffe: Legacy of the fifth Beatle 50 years after his death | url = http://www.liverpoolecho.co.uk/news/liverpool-news/stuart-sutcliffe-legacy-fifth-beatle-3346849 | work = Echo | first = Jade | last = Wright | name-list-style = vanc | date = 9 April 2012 }}</ref> * Raymond F. Boyce * John Ritter<ref>{{cite web|last=Considine|first=Bob|name-list-style=vanc|title=John Ritter's widow talks about wrongful death suit|url=http://www.today.com/id/22989512|publisher=today.com|date=4 February 2008|access-date=6 December 2016|archive-date=5 December 2014|archive-url=https://web.archive.org/web/20141205013834/http://www.today.com/id/22989512#.UpxHNOI8rIU}}</ref><ref>{{cite web|title=John Ritter: 1948–2003|url=http://www.people.com/people/article/0,,628262_2,00.html|archive-url=https://web.archive.org/web/20080320114343/http://www.people.com/people/article/0,,628262_2,00.html|archive-date=20 March 2008|publisher=[[People (magazine)|People]]|page=2|date=18 September 2003}}</ref> * Isabel Granada<ref>{{cite news|last1=Roxas|first1=Patricia Ann|title=Report: Isabel Granada in coma in Qatar hospital|url=http://entertainment.inquirer.net/247654/report-isabel-granada-coma-qatar-hospital|access-date=25 October 2017|work=Inquirer.net|date=25 October 2017}}</ref><ref>{{cite news|last1=ALG|title=Isabel Granada passes away in Qatar|url=http://www.gmanetwork.com/news/showbiz/chikaminute/631946/isabel-granada-passes-away-in-qatar/story/|access-date=5 November 2017|work=GMA News|date=5 November 2017}}</ref> * Geoffrey Thompson * Edwin Rosario * Joni Mitchell * Grant Imahara * Dr. Dre * Jovit Baldivino * Tom Sizemore == References == <references /> [[Category:Translated from MDWiki]] == External links == 2owir4slsu9p04k1jpoxqu9o28fc3b1 107900 107899 2026-07-25T23:40:46Z DaSupremo 9 Improve article 107900 wikitext text/x-wiki {{Databox}} An '''aneurysm''' be an outward [[:wikt:bulge|bulging]], dem liken to a bubble anaa balloon, wey a localized, abnormal, weak spot on a blood vessel wall cause.<ref>{{cite web|url=https://www.nhlbi.nih.gov/health-topics/aneurysm|archive-url=https://web.archive.org/web/20171222114406/https://www.nhlbi.nih.gov/health-topics/aneurysm|archive-date=22 December 2017|title=Aneurysms|website=Society of NeuroInterventional Surgery|access-date=23 February 2018}}</ref> Aneurysms fi be a result of a hereditary condition anaa an acquired disease. Aneurysms sanso fi be a [[wikt:Special:Search/nidus|nidus]] (starting point) for clot formation (thrombosis) den embolization. As an aneurysm dey increase in size, de risk of rupture dey increase, wich fi lead to uncontrolled bleeding.<ref>{{cite journal | vauthors = Cronenwett JL, Murphy TF, Zelenock GB, Whitehouse WM, Lindenauer SM, Graham LM, Quint LE, Silver TM, Stanley JC | title = Actuarial analysis of variables associated with rupture of small abdominal aortic aneurysms | journal = Surgery | volume = 98 | issue = 3 | pages = 472–83 | date = September 1985 | pmid = 3898453 }}</ref> Although dem fi occur insyd any blood vessel, particularly lethal examples include aneurysms of de circle of Willis insyd de brain, aortic aneurysms wey dey affect de thoracic aorta, den abdominal aortic aneurysms. Aneurysms fi arise insyd de heart following a heart attack, wey dey include both ventricular den atrial septal aneurysms. Der be congenital atrial septal aneurysms, a rare heart defect. ==Notable cases== <!-- This should only include either extremely notable individuals who died from routine aneurysms (e.g., Albert Einstein) or otherwise notable individuals who died from notable or rare aneurysms. Please do not include every instance of a notable individual who died from an aneurysm. --> * Senator Joe Biden. * Lucille Ball.<ref name="Lucille Ball dies">{{cite news |last=Ball |first=Lucille | name-list-style = vanc |title=Lucy dies |url=https://www.chicagotribune.com/1989/04/27/tvs-lucille-ball-dies-of-heart-failure-at-77/ |newspaper=[[Chicago Tribune]] |date=27 April 1989 |access-date=12 May 2013}}</ref><ref>{{cite web|url=http://www.highbeam.com/doc/1P2-1187461.html|archive-url=https://web.archive.org/web/20121106080946/http://www.highbeam.com/doc/1P2-1187461.html|archive-date=6 November 2012|title=Article: Lucille Ball, Pioneer of Television Comedy, Dies at 77|date=27 April 1989 |access-date=31 August 2009}}</ref><ref name="Ball Dies of Aorta Failure">{{cite news|last=Ball|first=Lucille| name-list-style = vanc |title=Ball dies of ruptured aorta|url=https://www.latimes.com/archives/la-xpm-1989-04-27-mn-1618-story.html |newspaper=Los Angeles Times |date=27 April 1989 |access-date=12 May 2013}}</ref> * Laura Branigan * David Cone * Davie Cooper * John Olerud * Albert Einstein<ref>{{cite web | title = Dr. Albert Einstein Dies in Sleep at 76; World Mourns Loss of Great Scientist | url = https://www.nytimes.com/learning/general/onthisday/bday/0314.html | date = 19 April 1955 | work = The New York Times }}</ref> * Thomas Mikal Ford * Charles de Gaulle.<ref>{{Cite web |last=Larousse |first=Éditions |title=Archive Larousse : Journal de l'année Édition 1971 - dossier - Dossier Charles de Gaulle 1890-1970, Un jour comme les autres |url=https://www.larousse.fr/archives/journaux_annee/1971/8/dossier_charles_de_gaulle_1890-1970 |access-date=2026-04-19 |website=Larousse.fr |language=fr}}</ref> * Richard Holbrooke<ref>{{cite web | title = US Diplomat Holbrooke dies after tearing arota | website = [[NBC News]] | date = 14 December 2010 | url = https://www.nbcnews.com/id/wbna40649624 }}</ref> * Édith Piaf * Stuart Sutcliffe<ref>{{cite web | title = Stuart Sutcliffe: Legacy of the fifth Beatle 50 years after his death | url = http://www.liverpoolecho.co.uk/news/liverpool-news/stuart-sutcliffe-legacy-fifth-beatle-3346849 | work = Echo | first = Jade | last = Wright | name-list-style = vanc | date = 9 April 2012 }}</ref> * Raymond F. Boyce * John Ritter<ref>{{cite web|last=Considine|first=Bob|name-list-style=vanc|title=John Ritter's widow talks about wrongful death suit|url=http://www.today.com/id/22989512|publisher=today.com|date=4 February 2008|access-date=6 December 2016|archive-date=5 December 2014|archive-url=https://web.archive.org/web/20141205013834/http://www.today.com/id/22989512#.UpxHNOI8rIU}}</ref><ref>{{cite web|title=John Ritter: 1948–2003|url=http://www.people.com/people/article/0,,628262_2,00.html|archive-url=https://web.archive.org/web/20080320114343/http://www.people.com/people/article/0,,628262_2,00.html|archive-date=20 March 2008|publisher=[[People (magazine)|People]]|page=2|date=18 September 2003}}</ref> * Isabel Granada<ref>{{cite news|last1=Roxas|first1=Patricia Ann|title=Report: Isabel Granada in coma in Qatar hospital|url=http://entertainment.inquirer.net/247654/report-isabel-granada-coma-qatar-hospital|access-date=25 October 2017|work=Inquirer.net|date=25 October 2017}}</ref><ref>{{cite news|last1=ALG|title=Isabel Granada passes away in Qatar|url=http://www.gmanetwork.com/news/showbiz/chikaminute/631946/isabel-granada-passes-away-in-qatar/story/|access-date=5 November 2017|work=GMA News|date=5 November 2017}}</ref> * Geoffrey Thompson * Edwin Rosario * Joni Mitchell * Grant Imahara * Dr. Dre * Jovit Baldivino * Tom Sizemore == References == <references /> [[Category:Translated from MDWiki]] == External links == {{sister project links||d=Q189389|c=Category:Aneurysms|n=no|b=no|q=no|v=no|voy=no|m=no|mw=no|s=no|wikt=Aneurysm|species=no}} * [http://www.angiocalc.com Brain aneurysm and percent packing calculator] {{Authority control}} [[Category:Gross pathology]] [[Category:Vascular diseases]] c8749p8lyux9o194l44ahhrwtn5ejww 0 28914 107901 2026-07-25T23:45:12Z DaSupremo 9 Created by translating the page "[[:en:Special:Redirect/revision/1365977078|Dedeiman]]" 107901 wikitext text/x-wiki '''Dedeiman''' be a community insyd de Ga West District of de Greater Accra Region of Ghana.<ref>{{Cite web |last=Sullemana |first=Malik |date=2020-03-30 |title=Court declares Nana Ekua Oyee family rightful owners of land at Dedeiman |url=https://ghanaiantimes.com.gh/court-declares-nana-ekua-oyee-family-rightful-owners-of-land-at-dedeiman/ |access-date=2026-07-25 |website=Ghanaian Times |language=en-US}}</ref> As at 2022, de Paramount Chief of de community be Nii Boye Akporsor I.<ref>{{Cite web |title=Accra: Dedeiman residents petition gov’t over activities of land guards |url=https://www.modernghana.com/news/1170656/accra-dedeiman-residents-petition-govt-over-acti.html |access-date=2026-07-25 |website=Modern Ghana |language=en}}</ref> As at 2026, de family head of de community be Abusuapanyin Nana Kwaku Nyarko II.<ref>{{Cite web |date=2026-02-23 |title=Onyaano/Dedeiman Community unveils a 10-Year transformational development plan |url=https://www.gbcghanaonline.com/news/onyaano-dedeiman-community-unveils-a-10-year-transformational-development-plan/2026/ |access-date=2026-07-25 |language=en-US}}</ref> == Education == Dedeiman M/A School dey locate insyd de community.<ref>{{Cite web |date=2021-01-29 |title=Ga West Assembly builds schools for five communities - MyJoyOnline |url=https://www.myjoyonline.com/ga-west-assembly-builds-schools-for-five-communities/ |access-date=2026-07-25 |language=en-US}}</ref> == Notable natives == * Beatrice Agbalenyo, Assembly member of de community.<ref>{{Cite web |last=Ametam |first=Dziffa Akua |date=2020-05-28 |title=Dziffa writes: I educated her as a child, she improved my livelihood as an adult; a true story of reciprocity |url=https://www.citinewsroom.com/2020/05/dziffa-ametam-writes-i-educated-her-as-a-child-she-improved-my-livelihood-as-an-adult-a-true-story-of-reciprocity/ |access-date=2026-07-25 |language=en-US}}</ref> == References == 2krkcfpld1q07d95l7y6vmqnwedd16p 107902 107901 2026-07-25T23:55:05Z DaSupremo 9 Improve article 107902 wikitext text/x-wiki {{Databox}} '''Dedeiman''' be a community insyd de Ga West District of de Greater Accra Region of Ghana.<ref>{{Cite web |last=Sullemana |first=Malik |date=2020-03-30 |title=Court declares Nana Ekua Oyee family rightful owners of land at Dedeiman |url=https://ghanaiantimes.com.gh/court-declares-nana-ekua-oyee-family-rightful-owners-of-land-at-dedeiman/ |access-date=2026-07-25 |website=Ghanaian Times |language=en-US}}</ref> As at 2022, de Paramount Chief of de community be Nii Boye Akporsor I.<ref>{{Cite web |title=Accra: Dedeiman residents petition gov’t over activities of land guards |url=https://www.modernghana.com/news/1170656/accra-dedeiman-residents-petition-govt-over-acti.html |access-date=2026-07-25 |website=Modern Ghana |language=en}}</ref> As at 2026, de family head of de community be Abusuapanyin Nana Kwaku Nyarko II.<ref>{{Cite web |date=2026-02-23 |title=Onyaano/Dedeiman Community unveils a 10-Year transformational development plan |url=https://www.gbcghanaonline.com/news/onyaano-dedeiman-community-unveils-a-10-year-transformational-development-plan/2026/ |access-date=2026-07-25 |language=en-US}}</ref> == Education == Dedeiman M/A School dey locate insyd de community.<ref>{{Cite web |date=2021-01-29 |title=Ga West Assembly builds schools for five communities - MyJoyOnline |url=https://www.myjoyonline.com/ga-west-assembly-builds-schools-for-five-communities/ |access-date=2026-07-25 |language=en-US}}</ref> == Notable natives == * Beatrice Agbalenyo, Assembly member of de community.<ref>{{Cite web |last=Ametam |first=Dziffa Akua |date=2020-05-28 |title=Dziffa writes: I educated her as a child, she improved my livelihood as an adult; a true story of reciprocity |url=https://www.citinewsroom.com/2020/05/dziffa-ametam-writes-i-educated-her-as-a-child-she-improved-my-livelihood-as-an-adult-a-true-story-of-reciprocity/ |access-date=2026-07-25 |language=en-US}}</ref> == References == <references /> [[Category:Towns insyd Ghana]] [[Category:Towns insyd Greater Accra Region]] [[Category:Populated places for Greater Accra Region insyd]] jyknis7fsf4vvy5hwdzp0rs1hcugqvd 14 28915 107905 2026-07-26T11:47:02Z DaSupremo 9 Fresh category 107905 wikitext text/x-wiki phoiac9h4m842xq45sp7s6u21eteeq1